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Antibody Mertansine (DM1) Conjugation Kit

  • CM11410: Antibody Mertansine (DM1) Conjugates
  • CM11410: Mertansine (DM1) Chemical Structure
Customer kit made to order, usually ships within 1-2 weeks
Calculated at checkout


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CellMosaic has designed this kit for antibody (IgG) labeling of mertansine (DM1) with SMCC (succinimidyl trans-4-(maleimidylmethyl)cyclohexane-1-carboxylate) linker for early stage screening of your antibody.

This kit includes SMCC and DM1, which can be coupled to the antibody sequentially via surface amines (a method developed by Immunogen). The product is purified to remove any unreacted drug. 

This kit provides materials to label one antibody. Scale of the reaction: 3 mg.

Drug Information

  • Name: Mertansine (DM1) 
  • CAS number: 139504-50-0
  • Mechanism of action: Inhibits cell division by blocking the polymerisation of tubulin

Key Features of this PerKit™

  • Offers a simple and easy way to label IgG with DM1 with minimum exposure to the toxin
  • Stable linkage 
  • Fast and easy preparation: 4 h preparation and <30 minutes hands-on time
  • All reagents and supplies included for preparation and purification
  • Over 90% pure conjugated products by SEC
  • Options to choose tailored services at CellMosaic after conjugation

After conjugation: you can choose to send your sample to CellMosaic for HPLC analysis and determination of the DOL.


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