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Biopolymer Labeling

CellMosaic labels biopolymers with either commercial or custom-made small molecules.

Small molecules (M2) that can be attached to a biopolymer include fluorescent compounds, chemiluminescent compounds, biotin, haptens, and other custom-made or commercial chemicals having carboxyl, primary amine, aldehyde/keto, hydroxyl, hydrazine/aminoxy, or thiol reactive functional group(s).

Typical biopolymers (M1) include antibodies, antibody fragments, enzymes (such as alkaline phosphatase and horseradish peroxidase,) proteins, peptides and peptidomimetics, DNA and DNA analogs, and avidin/streptavidin. L is the linker that connects M1 with M2, and n is the molar ratio of M2 to M1.