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Angiotensin II (1-8) (human, horse, sheep, pig, and rat)

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Product Sheet COA-0021033

Angiotensin II is the main effector peptide of the renin-angiotensin system. Angiotensin II binds two major receptors: the angiotensin II type-1 (AT1) receptor and type-2 (AT2) receptor.

Chemical Information

  • Chemical name: angiotensin II (1-8)
  • Sequence: Asp-Arg-Val-Tyr-Ile-His-Pro-Phe (or DRVYIHPF)
  • C-terminus: free acid;                   N-terminus: free amine
  • Counter ion: trifluoroactate salt;    Chemical formula: C50H71N13O12
  • Molecular weight:1046.19;           CAS number: 4474-91-3


  • Physical appearance: lyophilized powder;         Storage temp.: -20 °C
  • Purity: ≥ 96 % by HPLC


Recent reviews for Ang II:

  1. Lacolley P, Safar ME, Regnault V, Frohlich ED, AM J Physiol Heart Circ Physiol. 2009, 297, H1567-1575; 2. Palomeque J, Delbridge L, Petroff MV. Front Biosci. 2009 Jun 1;14:5118-33; 3. Chu KY, Leung PS. Curr Protein Pept Sci. 2009 Feb;10(1):75-84; 4. de Cavanagh EM, Ferder M, Inserra F, Ferder L. Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H550-8.

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