Angiotensin III (2-8) is generated from Ang II by aminopeptidase A. Ang III exerts its actions via the AT1 and AT2 receptors.

Chemical Information

• Chemical name: angiotensin III
• Sequence: Arg-Val-Tyr-Ile-His-Pro-Phe (or )
• C-terminus: free acid;       N-terminus: free amine
• Counter ion: trifluoroactate salt;    Chemical formula: C₄₆H₆₆N₁₂O₉
• Molecular weight: 931.09;    CAS number: 13602-53-4

Specification

• Physical appearance: lyophilized powder;         Storage temp.: -20 °C
• Purity: ≥ 98 % by HPLC

References

Recent reviews for Ang III:

1. Reaux-Le Goazigo A, Iturrioz X, Fassot C, Claperon C, Roques BP, Llorens-Cortes C. Curr Hypertens Rep.2005 Apr;7(2):128-34; 2. Reaux A, Fournie-Zaluski MC, Llorens-Cortes C. Trends Endocrinol Metab. 2001 May-Jun;12(4):157-62; 3. Yang CC, Kuo TB, Chan SH, Chan JY. Biol Signals. 1995 Mar-Apr;4(2):59-71.

Selected earlier papers for Ang III:

1. Vaughan ED Jr, Peach MJ. N Engl J Med. 1974 Nov 28;291(22):1193; 2. Goodfriend TL, Peach MJ. Circ Res. 1975 Jun;36(6 Suppl 1):38-48.