Angiotensin I (1-10) contains the peptide sequences necessary for all actions of the renin-angiotensin system, but it has little or no biologic activity. It converts to angiotensin II via the angiotensin converting enzyme.

Chemical Information

• Chemical name: angiotensin I
• Sequence: Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu (or DRVYIHPFHL)
• C-terminus: free acid;                   N-terminus: free amine
• Counter ion: trifluoroactate salt;    Chemical formula: C₆₂H₈₉N₁₇O₁₄
• Molecular weight: 1296.5;           CAS number: 484-42-4

Specification

• Physical appearance: lyophilized powder;         Storage temp.: -20 °C
• Purity: ≥ 96 % by HPLC

References

Recent reviews for Ang I:

1. Keidar S, Kaplan M, Gamliel-Lazarovich A. Carbiovasc Res. 2007, 73, 463-469; 2. Ferrario CM. J. Hypertens. 2002, 20, 805-807.