Alprenolol is an antagonist for ß1 and ß2 adrenergic receptors. Alprenolol agarose affinity chromatography was first introduced by Lefkowitz R. J. in 1979 for the purification of erythrocyte ß-adrenergic receptor based on ligand-receptor interactions. It is now routinely used for the purification of functionally active ß1 and ß2-adrenergic receptor.
Chemical Information
Alprenolol immobilized on agarose 4B beads through thiol ether linkage.
Specification
References