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    • Peptide and Protein
    • Kits
    • PerKit® KLH Universal Small Molecule Acid Conjugation Kit
  • Chemical structure of KLH Small Molecule Acid Conjugates generated using CM52426 PerKitKLH Universal Small Molecule Acid Conjugation Kit
  • Reaction chemistry/scheme for generating KLH Small Molecule Acid Conjugates using CM52426 PerKit KLH Universal Small Molecule Acid Conjugation Kit
  • workflow diagram of the protocol used in using CM52426 PerKit KLH Universal Small Molecule Acid Conjugation Kit
  • Chemical structure of KLH Small Molecule Acid Conjugates generated using CM52426 PerKitKLH Universal Small Molecule Acid Conjugation Kit Reaction chemistry/scheme for generating KLH Small Molecule Acid Conjugates using CM52426 PerKit KLH Universal Small Molecule Acid Conjugation Kit workflow diagram of the protocol used in using CM52426 PerKit KLH Universal Small Molecule Acid Conjugation Kit

    PerKit® KLH Universal Small Molecule Acid Conjugation Kit

    PerKit®

    MSRP:
    Now: $706.00
    (You save )
    SKU:
    CM52426
    Availability:
    In stock, usually ships within 24 hrs
    Shipping:
    Calculated at Checkout
    Reaction Scale:
    5 mg of KLH (provided in kit) and ≥1.8 µmol of small molecule acid (supplied by customer)

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    Product Description

    Download Documents
    SDS USER MANUAL

    Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein for antibody production. KLH is a large, oxygen-carrying, and multi-subunit protein that contains chelated copper of non-heme origin. CellMosaic® has designed this personalized KLH conjugation kit to work with any small molecule containing a carboxylic acid (-COOH) functional group. Using the kit components, the customer converts the carboxylic acid to an activated Sulfo N-hydroxysuccinimide (NHS) ester, followed by reaction with the surface amino groups of the protein to form a stable amide bond. The final product is purified to remove any unreacted small molecule acid. 

    This kit provides materials to perform one KLH labeling. Total amount of KLH included: 5 mg.


    Requirement for Small Molecule

    • Preferably contains only one carboxylic acid (-COOH)
    • Total amount: ≥ 1.8 µmol
    • Preferably > 90% pure
    • Absence of primary or secondary amine (-NH2) groups
    • The presence of the hydroxide (-OH) group will not affect the labeling

    Key Features of this PerKit™

    • Offers a simple and easy way to label KLH with any small molecule containing carboxylic acid
    • Fast and easy preparation: 4 hr preparation and <30 minutes hands-on time
    • All reagents and supplies included for preparation and purification
    • Over 90% pure conjugated products by SEC
    • Options to choose tailored services at CellMosaic® prior to and after conjugation

    Prior to conjugation: you can upload your small molecule information when you place your order. CellMosaic® will check if your molecule is compatible with this kit. 

    After conjugation: you can choose to send your sample to CellMosaic® for HPLC analysis.

     

    Product Videos

    Custom Field

    Reaction Scale 5 mg of KLH (provided in kit) and ≥1.8 µmol of small molecule acid (supplied by customer)

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