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    • Peptide and Protein
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    • BSA Conjugates
    • BSA-SN38 Conjugate
  • CM52149: BSA-SN38 Conjugate Structure
  • CM52149: BSA-SN38 Conjugate Structure

    BSA-SN38 Conjugate

    MSRP:
    Now: $594.00
    (You save )
    SKU:
    CM52149
    Availability:
    In stock, usually ships within 24 hrs
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    • Overview

    Product Description

    Download Documents
    Product Sheet
    SDS COA Lot S585.S8.0306E

    SN38, the active metabolite of irinotecan, is a chemotherapeutic agent primarily used for colorectal cancer treatment. As a topoisomerase I inhibitor, SN38 interferes with DNA replication, ultimately leading to cancer cell death. The BSA-SN38 conjugate is designed using linker chemistry similar to that of ADCs and PDCs which can be produced using our SN38 Conjugation Kits (Cat#: CM11408, CM11430). It is synthesized at CellMosaic and intended for immunization or immunoassay applications. The final conjugate is lyophilized from a citrate buffer for convenient shipping, storage, and reconstitution

    The product is sold as either 1 vial of 1 mg (Cat# CM52149-1MG) or 5 vials of 1 mg (Cat# CM52149-5MG). For bulk orders, please contact us for a quote.


    Application

    • Assay development for detection of SN38 or SN38 metabolites in vitro or in vivo. 
    • Antibody discovery via immunization and hapten recognition
    • Indirect and competitive ELISA assay

    Key Features

    • Lyophilized powder and ready for usage after reconstitution with water, no need for external buffer.
    • Optimized loading with an average 3 to 5 SN38 molecules per BSA
    • Amount accurately determined by UV/HPLC analysis.

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