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Antibody Drug Conjugate Kits!
AqT bioconjugates coming soon!
CellMosaic offers bioassay services that are directly related to the quality of the bioconjugates we manufacture in-house. These assays are usually an integral part of our bioconjugation services. The following are the typical bioassays we perform:
Functional Group Assays
One of the key elements of bioconjugation is understanding the characteristics of the biopolymers involved and quantifying their functional groups.
For example, if cysteine (Cys) residues are used in a bioconjugation reaction, it is good practice to determine the amount of reactive Cys present, as free thiols are easily oxidized in air.
Similarly, if a drug is conjugated to a protein through surface amine groups, quantifying the free amine content before and after conjugation allows determination of drug loading.
Biopolymer Activity Assays
Enzymatic activity assays such as HRP or AP, or biotin assays for biotinylated biopolymers.
Fluorescence Assays
For biopolymers labeled with fluorescent dyes.
Endotoxin Assays
Measurement of endotoxin levels in bioconjugates.
Please contact us if you have specific bioassay needs or would like to discuss a customized testing plan.
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