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PerKit™ Virus Small Molecule Acid Conjugation Kit

  • Virus Small Molecule Acid Conjugation Kits
Price:
$377.00
SKU:
CM55401
Availability:
Made to order, usually ships within 1-3 days
Shipping:
Calculated at checkout
Describe your small molecule:

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Or upload your small molecule structure:

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SDS USER MANUAL

This is a personalized conjugation kit (PerKit™) for virus particles labeling of a small molecule containing carboxylic acid (-COOH) functional groups (total amount of virus particles is in the range of 10^11 particles or less). Using the kit components, the customer converts the carboxylic acid to an activated N-hydroxysuccinimide (NHS) ester, followed by reaction with the surface amino groups of the proteins of the virus particle to form a stable amide bond. The final product is desalted to remove any unreacted small molecule acid. 


Requirement for Small Molecule

  • Preferably > 90% pure
  • Absence of primary or secondary amine (-NH2) groups
  • Preferably contains only one non-hindered aliphatic carboxylic acid (-COOH)
  • For molecule containing aromatic carboxylic acid, hindered aliphatic carboxylic acid, or hydroxyl (-OH) groups, please consult CellMosaic first before placing the order.

Key Features of this PerKit™

  • Offers a simple and easy way to label virus particle with any small molecule containing carboxylic acid
  • Fast and easy preparation: 4 h preparation and <30 minutes hands-on time
  • All reagents and supplies included for preparation and purification
  • Covalent attachment with stable bond
  • Options to choose tailored services at CellMosaic prior to conjugation

Prior to conjugation: you can upload your small molecule information when you place your order. CellMosaic will general a PerKit™ sheet containing calculation, chemical structure, MW of your final conjugate, and recommendations for the conjugation if your molecule has special features. 


Protocol

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Labeling Chemistry

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