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Oligo—Half Antibody Conjugate

  • Image 1
  • Scheme: reduced IgG reaction with a maleimide activated oligo
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Product Description

  • Chemistry: Antibody is reduced at the hinge region to yield two half-antibody molecules which then react with maleimide-activated oligos.
  • Specification: A pool of heterogeneous products.
  • Procedure: After a buffer exchange (if necessary), labeling of amine modified-oligos with NHS ester-maleimide followed by gel filtration to remove excess crosslinking reagents. Then reduction of antibody followed by conjugation of antibody to maleimide-activated oligos and purification. Finally, concentration determination and gel electrophoresis analysis of the oligo-half antibody conjugates.
  • Price: please contact us for a quote.
  • Starting materials: Please check biopolymer for ordering information.

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